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So iconic is Brundle’s change that it inspired Demi Moore’s transformation in upcoming horror movie The Substance.

“At first, he has hair on his back.

Demi Moore behind the scenes of The Substance

He’s losing one nail.

It’s a small decay.

It’s step by step.

Demi Moore behind the scenes of The Substance

He’s not suddenly gruesome.

So it was trying to find the right balance.

For Moore, the prosthetics experience was a significant first.

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“It was also a part of what was enticing and exciting.

The team was incredibly talented.

But it’s time-consuming.

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It really does require that you get very Zen, to be still.

And it was such an important part and a unique way of telling this story.”

The Substance is released on September 20.

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